Aging and the Heart: A Post-Genomic View by José Marín-García M.D., Michael J. Goldenthal, Gordon W. Moe

By José Marín-García M.D., Michael J. Goldenthal, Gordon W. Moe (auth.)

Cardiac getting older, like getting older normally, is a posh method. a number of mobile and molecular alterations give a contribution to the expression of the a number of phenotypes of getting older, "the varied faces" of cardiac getting older. during this publication, the genetic and molecular foundation of cardiovascular getting older could be mentioned. moreover, a entire evaluation of the bioenergetic alterations that take place in human and animal types of cardiac getting older in addition to present diagnostic and destiny healing modalities should be undertaken.

José Marín-García is Director, The Molecular Cardiology and Neuromuscular Institute, Highland Park, New Jersey.

Show description

Read Online or Download Aging and the Heart: A Post-Genomic View PDF

Similar nonfiction_9 books

Nicotinoid Insecticides and the Nicotinic Acetylcholine Receptor

The nicotinoids are an important new category of insecticides, becoming a member of the organophosphorus compounds, methylcarbamates, and pyrethroids because the significant pesticides. lately, imidacloprid and similar nicotinoids have all started changing organophosphorus and methylcarbamate compounds as pesticides to regulate insect pests on significant plants.

The Welfare of Pigs

The household pig is perceived as an animal with intelligence and personality and but, within the industrialized global, the vast majority of humans have had very little touch with them. Pigs are topic to a variety of environments from the tropics to the sub-arctic, starting from small-scale, huge platforms to large-scale in depth platforms.

Grune Gentechnik im Widerstreit: Modell einer partizipativen Technikfolgenabschatzung zum Einsatz transgener herbizidresistenter Pflanzen

Content material: bankruptcy 01 Technikfolgenabschatzung als politisches scan (pages 2–40): Wolfgang van den Daele, Alfred Puhler and Herbert SukoppChapter 02 Zusammenfassung der Ergebnisse des TA? Verfahrens (pages 41–56): Wolfgang van den Daele, Alfred Puhler and Herbert SukoppChapter 03 Die Ausgangskontroverse: Evolutionsbiologische Argumente in der Risikodiskussion am Beispiel der transgenen herbizidresistenten Pflanzen (Kurzfassung des Gutachtens) (pages 57–68): Barbara WeberChapter three.

NMR Spectroscopy: Processing Strategies, Second Updated Edition

Textual content for the sequence "Spectroscopic Techniques": major software program designers and academics of spectroscopy have pooled their services to plan a brand new sequence "Spectroscopic recommendations: An Interactive Course". consumer may be able to achieve a greater figuring out of numerous spectroscopic suggestions in those step by step courses.

Additional resources for Aging and the Heart: A Post-Genomic View

Example text

Biodemographic trajectories of longevity. Science 1998;280:855–860 4. Perls TT, Bubrick E, Wager CG, Vijg J, Kruglyak L. Siblings of centenarians live longer. Lancet 1998;351:1560 5. Gudmundsson H, Gudbjartsson DF, Frigge M, Gulcher JR, Stefansson K. Inheritance of human longevity in Iceland. Eur J Hum Genet 2000;8:743–749 6. Carmelli, D. Intrapair comparisons of total life span in twins and pairs of sibs. Hum Biol 1982;54:525–537 7. Yashin AI, Iachine IA, Harris JR. Half of the variation in susceptibility to mortality is genetic: findings from Swedish twin survival data.

Adv Gerontol 2004;14:7–20 71. Charlesworth B. Fisher, Medawar, Hamilton and the evolution of aging. Genetics 2000;156:927–931 72. Rose MR. The evolutionary biology of aging. Oxford: Oxford University Press; 1991, Chapter 1 73. Comfort A. The biology of senescence. Edinburgh, UK: Churchill Livingstone; 1979 74. Gavrilov LA, Gavrilova NS. The biology of life-span: a quantitative approach. Switzerland: Harwood, Chur; 1991 75. Wachter KW, Finch CE. Between Zeus and the Salmon: the biodemography of longevity.

In vitro senescence occurring in normal human endothelial cells can be rescued by ectopic telomerase activity. Transplant Proc 2003;35:2483–2485 89. Steinert S, Shay JW, Wright WE. Transient expression of human telomerase extends the life span of normal human fibroblasts. Biochem Biophys Res Commun 2000;273:1095–1098 90. Yang J, Chang E, Cherry AM, Bangs CD, Oei Y, Bodnar A, Bronstein A, Chiu CP, Herron GS. Human endothelial cell life extension by telomerase expression. J Biol Chem 1999;274:26141–26148 91.

Download PDF sample

Rated 4.28 of 5 – based on 30 votes