By Robert K.M. Hay, Jae-Gahb Park, Adi Gazdar
Human tumor cells in tradition are precious for learning melanoma factors and houses. this useful reference presents important details for melanoma researchers on everyday, proven tumor telephone strains of the key human organ systems.
Atlas of Human Tumor telephone Lines comprises information approximately morphological, metabolic, genetic, and development features of human tumor cells, with morphological features awarded in additional than 250 photomicrographs. It additionally comprises details for developing and preserving human tumor phone traces in tradition, and every bankruptcy covers destiny views.
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* Covers well-characterized tumor mobile strains from the foremost human organ systems
* provides over 250 photomicrographs, either phase-contrast and electron micrographs
* incorporates a checklist of key references for every chapter
* Written by way of world-renowned experts
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Extra info for Atlas of Human Tumor Cell Lines
Example text
1987). , 1989). , 1990). Given the finding that Sevenless has a specific function in one particular cell type in the developing eye of the fruit fly, the selective expression of c-ros mRNA in glioma cell lines is certainly an intriguing finding. Even more intriguing is the finding that c-ros mRNA does not seem to be expressed in gliomas in vivo (Wu and Chikaraishi, 1990) or in the mammalian nervous system during development. , 1991). Searches for other abnormalities in structure or expression of oncogenes and proto-oncogenes in human glioma cell lines have yielded a relatively incoherent picture.
And Mark, J. (1984). Chromosomes and chromosomal progression of human gliomas in vivo, in vitro and in athymic nude mice. Prog. Exp. Tumor Res. 27, 67-82. Bigner, S. , Mahaley, M. , and Bigner, D. D. (1984). Patterns of the early gross chromosomal changes in malignant human gliomas. Hereditas 101, 103-113. Bigner, S. , Schold, S. , and Bigner, D. D. (1985). A serially transplantable human giant cell glioblastoma that maintains a near-haploid stem line. Cancer Genet. Cytogenet. 18, 141-154. Bigner, S.
Acad. Sei. A. 86, 7186-7190. , Robbins, K. , Andersen, P. , Tronick, S. , Reddy, E. , Ellmore, N. , Galen, A. , Lantenberger, J. , Papas, T. , Westin, E. , Gallo, R. , and Aaronson, S. A. (1982). Cellular genes analogous to retroviral one genes are transcribed in human tumour cells. Nature (London) 295, 116-119. Fleming, T. , Clark, W. C, Robertson, J. , Oldfield, E. , Aaronson, S. , and Ali, I. U. (1992a). Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors.