By Tobias A. Oelschlaeger, Jörg H. Hacker
This newest quantity within the very good Subcellular Biochemistry sequence is the 1st try and supply an in-depth assessment of the sector of bacterial mobile invasion. the present wisdom approximately all well-studied micro organism being able to invade eukaryotic cells is introduced jointly, together with micro organism pathogenic to people and animals in addition to the symbiotic rhizobia. numerous chapters additionally take care of new ways and purposes concerning invasive micro organism.
The booklet, inclusive of contributions from around the world specialists, discusses bacterial invasion skill in the context of bacteria-host cellphone interplay with the main target on pathogenicity.
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Extra resources for Bacterial Invasion into Eukaryotic Cells: Subcellular Biochemistry
1990), newborn meningitis-causing E. , 1996), K. , 1995). , 1998). , 1995). Similarly, engulfment of L. monocytogenes by P338D1 macrophages is sensitive to treatment with cytochalasin D as well as colchicine and nocodazole, but not to taxol (Kuhn, 1998). The specific requirements for the host cell cytoskeleton depend not only upon the bacterial strain, but also upon the type of host cell utilized. , 1993). e. MT-dependent alone, or MF-dependent uptake) that recognize different host receptors which are not expressed on all host cell types.
1993). e. MT-dependent alone, or MF-dependent uptake) that recognize different host receptors which are not expressed on all host cell types. Tobias A. Oelsdllaeger and Dennis J. Kopecko 6 Unidirectional movement and/or depolymerization of MT results in membrane invagination and internalization of attached bacterium A inside CM outside ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ J ( -l-l-l-l-l-l-l-l-l-l-l I~ · Movement of activated molecular ,;; motor connected to membrane 1~ receptor causes invagination and e internalization of adjacent pathogen B inside CM outside FIGURE 1.
1997, Acidic sphingomyelinase mediates entry of N. gonorrhoeae into nonphagocytic cells, Cel/91:605-615. , Gonococcal opacity protein promotes bacterial entry-associated rearrangement of the epithelial cell actin cytoskeleton, Infect. lmmun. 64:1621-1630. , 1997, CD66 carcinoembryonic antigens mediate interaction between Opa-expressing Neisseria gonorrhoeae and human polymorphonuclear phagocytes, EMBO J. 16:3435-3445. , 1997, Dr fimbriae operon of uropathogenic Escherichia coli mediate microtubule-dependent invasion to the HeLa epithelial cell line, J.