Bone Marrow Diagnosis: An Illustrated Guide, Second Edition

Bone Marrow Diagnosis is an important source for all those that have to record bone marrow trephine biopsies. The textual content is succinct and concentrates at the center info essential to make a correct analysis. every one diagnostic entity is observed by means of top of the range photographs which exhibit commonplace and more odd examples of histological beneficial properties. This new version has been thoroughly revised and up to date all through and contains many new photographs together with stipulations now not illustrated within the first edition.

A easily written and well-illustrated textual content for the busy diagnostician

  • Every part comprehensively revised by means of foreign group of authors
  • Over 900 prime quality color pictures to accompany every one diagnostic entity
  • Coverage of cytology in sections in relation to myeloid dysplasias and acute leukemias
  • Incorporates new WHO class of lymphomas and leukemias
  • Author workforce improved to incorporate specialists from Stanford collage, California

Chapter 1 advent (pages 1–4):
Chapter 2 the conventional Bone Marrow (pages 5–19):
Chapter three Human Immunodeficiency Virus an infection (pages 20–30):
Chapter four Anemias and Aplasias (pages 31–40):
Chapter five The Myelodysplastic Syndromes (pages 41–47):
Chapter 6 Myeloproliferative disorder (pages 48–69):
Chapter 7 Acute Leukemia (pages 70–89):
Chapter 8.1 Lymphomas (pages 90–101):
Chapter 8.2 Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (pages 102–108):
Chapter 8.3 persistent Lymphocytic Leukemia (pages 109–115):
Chapter 8.4 Lymphoplasmacytic Lymphoma (Including Waldenstrom Macroglobulinemia) (pages 116–121):
Chapter 8.5 Mantle mobilephone Lymphoma (pages 122–125):
Chapter 8.6 Follicular Lymphoma (pages 126–131):
Chapter 8.7 Marginal quarter B telephone Lymphoma (Including Malt sort) (pages 132–134):
Chapter 8.8 furry mobile Leukemia (pages 135–141):
Chapter 8.9 a number of Myeloma (pages 142–152):
Chapter 8.10 Diffuse huge B telephone Lymphoma (pages 153–158):
Chapter 8.11 Burkitt Lymphoma (pages 159–164):
Chapter 8.12 huge Granular Lymphocyte Leukemia (pages 165–167):
Chapter 8.13 Cutaneous T cellphone Lymphoma (pages 168–169):
Chapter 8.14 Peripheral T mobile Lymphomas, Unspecified (pages 170–172):
Chapter 8.15 Hepatosplenic T mobilephone Lymphoma (pages 173–174):
Chapter 8.16 Angioimmunoblastic T mobilephone Lymphoma (pages 175–177):
Chapter 8.17 grownup T telephone Lymphoma/Leukemia (pages 178–179):
Chapter 8.18 Anaplastic huge mobilephone Lymphoma (pages 180–182):
Chapter nine Hodgkin Lymphoma (pages 183–189):
Chapter 10 Metastatic sickness (pages 190–196):
Chapter eleven Miscellaneous (pages 197–208):
Chapter 12 Technical issues (pages 209–213):

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Extra resources for Bone Marrow Diagnosis: An Illustrated Guide, Second Edition

Sample text

The fungi Cryptococcus (Fig. 14) and Histoplasma (Fig. 15) and the protozoan Leishmania (Fig. 16) are usually found in reactive macrophages often associated with granuloma formation (Fig. 17). Cytomegalovirus (CMV) infection can be detected by characteristic nuclear inclusions, particularly within endothelial cells (Fig. 18). 1 26 Chapter 3 Fig. 13 Atypical tuberculosis in HIV marrow not associated with granulomas. ZN stain. (a) (b) Fig. 14 HIV-associated cryptococcal infection. (a) H&E. (b) Mucicarmine.

13 Typical histologic appearances of ET shown by Giemsa (left and centre) and H&E (right) on top row. The abnormal megakaryocytes are highlighted by immunostaining for CD31 (middle row) and CD61 (bottom row). Note in both the high power Giemsa and immunostains that abnormal megaplatelets can be detected within the cytoplasm of the larger megakaryocytes. This is a feature rarely seen in reactive megakaryocytes. 56 Chapter 6 Fig. 14 Megakaryocytes clustering around dilated sinuses. Giemsa. Fig. 15 Fibrosis associated with abnormal megakaryocytes in ET.

Immunostained for glycophorin C to outline erythroid colonies. 31 32 Chapter 4 low power Fig. 2 Anemia of chronic disease. Normal cellularity for age shown at low and higher powers. H&E. Iron may be seen in macrophages staining green on Giemsa. higher power H&E (a) Giemsa (b) Fig. 3 Autoimmune hemolytic anemia. (a) Hypercellular marrow. (b) Erythroid hyperplasia. Giemsa. Anemias and aplasias (a) (c) (b) (e) 33 (d) (f) Fig. 4 Typical megaloblastic anemia. (a) Cytology. (b) Low power. (c,d) High power, (e,f) Immunostains for glycophorin C to highlight erythroid cells.

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