By Clifford P Stanners
Considers the hot explosion of information in regards to the carcinoembryonic antigen (CEA) kinfolk, which resulted from the molecular cloning of friend genes in 1986.
Results indicating CEA kinfolk upregulated in melanoma can have an instrumental position in malignant transformation and metastasis, whereas those who are downregulated can have tumor suppressive capabilities are thought of. experiences, fresh effects, hypotheses, and medical purposes relating to a gene family members that, from its frequent adjustments in expression in tumors at many websites, may be considered as a "major participant" in human melanoma also are mentioned. the conventional features corresponding to epithelial and hematopoietic adhesion and signalling molecules are explored, and the potentially exact function of this kin in evolution is brought.
This quantity may be of curiosity to researchers within the fields of intercellular adhesion, evolution, and molecular acceptance, in addition to clinicians drawn to the new wisdom concerning a tumor marker as a rule utilised within the sanatorium, and corporations wishing to take advantage of this cancer-related kinfolk for novel advertisement purposes within the biomedical sphere.
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Additional resources for Cell adhesion and communication mediated by the CEA family : basic and clinical perspectives
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