Evolution equations and their applications in physical and by Lumer G., Weis L. (eds.)

By Lumer G., Weis L. (eds.)

This quantity offers a set of lectures on linear partial differntial equations and semigroups, nonlinear equations, stochastic evolutionary techniques, and evolution difficulties from physics, engineering and mathematical biology. The contributions come from the sixth overseas convention on Evolution Equations and Their functions in actual and lifestyles Sciences, held in undesirable Herrenalb, Germany.

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Evolution equations and their applications in physical and life sciences

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2005; Frenkel and Solomon 2002) and may therefore be exploited for CNS drug and gene delivery. Drug addiction is an important health and social problem world-wide, a prevailing culprit of which is the highly addictive recreational drug cocaine. It has been previously shown that protein-based therapeutics designed to bind to cocaine can reduce the drug load and attenuate its psychoactive effects. However, this strategy has not generally demonstrated significant therapeutic value due to the inability of these cocaine-binding proteins to cross the BBB and gain access to the CNS.

Alternatively, the addition of polyethylene glycol (PEG) can also improve phage circulation (Kim et al. 2008). While the simplicity of phages positions them as attractive cloning vectors, they are generally limited by the size of the gene(s) of interest that can be cloned into the phage head, and in most cases lack natural nuclear honing and expression abilities in eukaryotic cells (Clark et al. 2011; Larocca and Baird 2001). While filamentous bacteriophage have a far more flexible packaging minimum and maximum (Specthrie et al.

Hubbell, J. A. (1992). Surface-immobilized polyethylene oxide for bacterial repellence. Biomaterials, 13(7), 417–420. Donlan, R. M. (2001). Biofilms and device-associated infections. Emerging Infectious Diseases, 7(2), 277–281. Donlan, R. M. (2009). Preventing biofilms of clinically relevant organisms using bacteriophage. Trends in Microbiology, 17(2), 66–72. , Rosdahl, V. , & Skinhøj, P. (1994). Effect of treatment with methicillin and gentamicin in a new experimental mouse model of foreign body infection.

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